Join a Research Study

The COMP006 Study

Exploring Potential New Routes Away From Treatment-Resistant Depression


Many people who receive antidepressant treatment for their depression do not get an adequate response to the medicines they are taking. If someone is taking two or more antidepressants and they are failing, this is sometimes referred to as treatment-resistant depression or TRD.

Introducing the COMP006 Study

The COMP 006 study is looking into a new treatment approach for people with TRD using an investigational medicine given with psychological support. The study is suitable for people who have been diagnosed with major depression and are currently experiencing a recurrent or single episode of depression but that have not responded to antidepressant treatment.


    You may be eligible to participate in a Compass Pathfinder study if you:
  • Are 18 years of age or older
  • Have been diagnosed with major depression (single or recurrent episodes)
  • Are experiencing treatment-resistant depression, defined as failing 2, 3 or 4 pharmacological treatments for your current episode of depression
  • Meet additional study criteria.

About the Study


COMP006 is a three-part study which will last up to 62 weeks.


Participants will receive support from study clinicians to help them withdraw off any prohibited medications, including current antidepressants. Participants will be asked to remain off prohibited medications for parts of the study under close medical supervision.


Reimbursement for reasonable, out-of-pocket expenses for travel and other expenses may be available to qualified individuals.  

More Information

If you are interested in learning more about the COMP006 study, please contact us for an informal chat at:


E-mail: contact@gminstitutes.comCall: 609-921-6050 – Text: 609-921-3555

We will ask you some brief questions and provide additional information about the study.


Expressing an interest does not oblige you in any way to take part in the study. So please, do get in touch if you want to find out more.

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